Prescription Strength Products
Iontosone™
- Ingredients
- How it Works
Iontosone™ 0.4% dexamethasone sodium phosphate solution is a prescription corticosteroid formulation commonly used in physical therapy and sports medicine settings, particularly for iontophoresis-assisted delivery.
It is used to help reduce localized inflammation, pain, and swelling associated with musculoskeletal conditions.
Iontosone™ may be used for:
- Tendinitis and tendinopathy
- Bursitis
- Epicondylitis (e.g., tennis elbow)
- Plantar fasciitis
- Localized soft tissue inflammation
- Inflammatory conditions treated during physical therapy
This formulation is intended for localized treatment, allowing anti-inflammatory therapy to be delivered directly to the affected area rather than systemically.

RX Only medications can only be ordered by healthcare providers when it is determined the product is clinically significant over other available products
Nubratori RX™ Products are produced and lawfully sold in the USA, under the FDA Structured Product Listing Marketing Category #C181659 “Outsourcing Facility Compounded Human Drug Product” (Exempt From Approval Requirements). Outsourcing Facility products have not been evaluated by the FDA for pre-market approval. Pursuant to federal law, this drug is exempt from the FD&C Act: section 505 (21U.S.C. 355) (concerning the approval of new drug applications or abbreviated new drug applications). This information provided is not intended to be viewed by the general public or consumers. It is intended for properly licensed Health Care Professionals.
Dexamethasone sodium phosphate is a potent corticosteroid that exerts anti-inflammatory effects by modulating gene expression involved in inflammatory pathways.
Its actions include:
- Inhibition of phospholipase A₂
- Reduced production of prostaglandins and leukotrienes
- Decreased inflammatory cytokine activity
- Reduced capillary permeability and tissue edema
When administered via iontophoresis, the negatively charged dexamethasone phosphate molecule is driven through the skin using a low-voltage electrical current, allowing targeted transdermal delivery into superficial tissues.
Why Iontophoresis with Dexamethasone?
Using iontophoresis allows:
- Localized corticosteroid delivery without injection
- Reduced systemic corticosteroid exposure
- Targeted treatment of superficial inflammatory conditions
- Integration into physical therapy treatment plans
Iontosone™ 0.4% is formulated specifically for compatibility with iontophoresis protocols commonly used in rehabilitation and sports medicine.



